Differing Strategies Despite Shared Lineages of Motor Neurons and Glia to Achieve Robust Development of an Adult Neuropil in Drosophila.

Differing strategies used by motor neurons and glia to achieve robust development of an adult neuropil in Drosophila

Delta expression in post-mitotic neurons identifies distinct subsets of adult-specific lineages in Drosophila.

The Drosophila ventral nerve cord is comprised of numerous neuronal lineages, each derived from a stereotypically positioned neuroblast (NB). At the embryonic stage the unique identities of each NB, and several of their neuronal progeny, are well characterized by spatial and temporal expression patterns of molecular markers. These patterns of expression are not preserved at the larval stage and...

Adult Hippocampal Neurogenesis and Memory

Adult neurogenesis, a concept emergent in the late 1990s, is the generation of new neurons in the adult brain. This process occurs thank to cells who have this proliferative feature, named as Neural Stem Cells (NSCs). Neural Stem Cells (NSCs) are primary progenitors who can generate the two neural types (neurons and glia). Classically it was assumed that NSCs are only present in the embryo, but...

Larval Brain

I n this chapter we will start out by describing in more detail the progenitors of the nervous system, the neuroblasts and ganglion mother cells.Subsequentlywe will survey the generic cell types that make up the developing Drosophila brain, namely neurons, glial cells and tracheal cells.Finally,we will attempt a synopsis ofthe neuronal connectivity ofthe larval brain that can be deduced from th...

Segregation of postembryonic neuronal and glial lineages inferred from a mosaic analysis of the Drosophila larval brain

Due to its intermediate complexity and its sophisticated genetic tools, the larval brain of Drosophila is a useful experimental system to study the mechanisms that control the generation of cell diversity in the CNS. In order to gain insight into the neuronal and glial lineage specificity of neural progenitor cells during postembryonic brain development, we have carried an extensive mosaic anal...